AllerGAtlas 1.0: a human allergy-related genes database
Jinying Liu1#, Yuan Liu2#, Dan Wang2#, Mengqi He2, Lihong Diao2, Li Tang2, Fuchu He2, Dong Li2* and Shuzhen Guo1*
1 School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
2 State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences-Beijing (PHOENIX Center), Beijing Institute of Lifeomics, Beijing, China
* Correspondence: Shuzhen Guo, Ph.D., School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China. Tel: +86 10 64286192; Fax: +86 10 64286192; E-mail: email@example.com
Correspondence may also be addressed to Dong Li, Ph.D., State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Science-Beijing (PHOENIX Center), Beijing Institute of Lifeomics, Beijing 102206, China; Tel: +86 10 61777057; Fax: +86 10 61777057; E-mail: firstname.lastname@example.org
# These authors contributed equally to this work.
Allergy is a detrimental hypersensitive response to innocuous environmental antigen, which is caused by the effect of interaction between environmental factors and multiple genetic predisposition. In the past decades, hundreds of allergy-related genes have been identified to illustrate the epidemiology and pathogenesis of allergic diseases, which are associated with better endophenotype, novel biomarkers, early-life risk factors and individual differences in treatment responses. However, the information of all these allergy-related genes is dispersed in thousands of publications. Here we present a manually curated human allergy-related gene database of AllerGAtlas, which contained 1,195 well-annotated human allergy-related genes, determined by text-mining and manual curation. HisgAtlas will be a valuable bioinformatics resource to search human allergy-related genes and explore their functions in allergy in experimental research.
Database URL: http://biokb.ncpsb.org/AlleRGatlas/
Keywords: allergy; gene; database; text-mining; manual curation